- 26 October 2025, Atletico Nacional Medellin vs Independiente Medellin, 5-2, Lose
 - 21 October 2025, Independiente Medellin vs Independiente Santa Fe, 1-1, Draw
 - 17 October 2025, Independiente Medellin vs Fortaleza CEIF, 3-1, Win
 - 13 October 2025, Once Caldas vs Independiente Medellin, 1-5, Win
 - 08 October 2025, Aguilas Doradas Rionegro vs Independiente Medellin, 2-1, Lose
 
- 25 October 2025, America de Cali vs Atletico Junior Barranquilla, 2-1, Win
 - 19 October 2025, Deportivo Cali vs America de Cali, 0-2, Win
 - 12 October 2025, America de Cali vs La Equidad Seguros, 3-2, Win
 - 08 October 2025, Millonarios FC vs America de Cali, 2-1, Lose
 - 28 September 2025, America de Cali vs Envigado FC, 1-1, Draw
 
In the Primera A competition match on 07 December 2023, Independiente Medellin emerged victorious on their home ground, besting America de Cali in a 2-1 showdown. Despite the closely matched balance of yellow cards, Independiente Medellin showcased exceptional tactical prowess to edge out their opponents.
One notable observation in this match was the early scoring pattern displayed by both teams. Independiente Medellin had a fast start, with their first goal recorded merely 25 minutes and 33 seconds into the first half, taking an early lead. However, America de Cali responded swiftly, equalizing with a goal just seven minutes later at the 32nd minute. Independiente Medellin though, did not let the equalizer dampen their drive, responding with a second goal just six minutes later.
America de Cali showed strong control during the match, reflected in their count of 7 corner kicks compared to Independiente Medellin's 4. However, the home team was able to effectively manage these threats, preventing any goals from these set-pieces.
The discipline of both teams was relatively evenly matched, with both accumulating two yellow cards each. Independiente Medellin received their bookings later into the game, both in the second half, possibly due to pressure to maintain their 2-1 lead.
Interestingly, the offside statistics presented a different story. Independiente Medellin was caught offside thrice, suggesting their aggressive approach and eagerness to penetrate the defensive line of the away team. On the other hand, America de Cali did not record any offsides, suggesting a more cautious approach in their gameplay.
In conclusion, while America de Cali seemed to have a more controlled game in terms of corner kicks and offsides, they were not able to capitalize on these opportunities. Independiente Medellin, on the other hand, capitalized on their chances early in the game and defended well to maintain their lead. These factors significantly impacted the final outcome of the match, proving that taking timely advantage of scoring opportunities can lead to positive results despite statistical disadvantages in other areas of play.
Form Guide
| Lose | 5-2 | Atletico Nacional Medellin vs Independiente Medellin | |
| Draw | 1-1 | Independiente Medellin vs Independiente Santa Fe | |
| Win | 3-1 | Independiente Medellin vs Fortaleza CEIF | |
| Win | 1-5 | Once Caldas vs Independiente Medellin | |
| Lose | 2-1 | Aguilas Doradas Rionegro vs Independiente Medellin | 
- PLAYED
 - 5
 
- WINS
 - 2
 
- GOALS
 - 12:10
 
- GOALS / MATCH
 - 2.4
 
- Independiente Medellin has two wins in its last five matches with a goal difference of 12:10, scoring 2.4 goals average
 
| Win | 2-1 | America de Cali vs Atletico Junior Barranquilla | |
| Win | 0-2 | Deportivo Cali vs America de Cali | |
| Win | 3-2 | America de Cali vs La Equidad Seguros | |
| Lose | 2-1 | Millonarios FC vs America de Cali | |
| Draw | 1-1 | America de Cali vs Envigado FC | 
- PLAYED
 - 5
 
- WINS
 - 3
 
- GOALS
 - 9:6
 
- GOALS / MATCH
 - 1.8
 
- America de Cali has won three out of its last five matches with a goal difference of 9:6, scoring 1.8 goals average
 
Independiente Medellin H2H America de Cali
| Away game | Independiente Medellin | 1 | 1 | America de Cali | Home game | Primera A | |
| Home game | Independiente Medellin | 1 | 1 | America de Cali | Away game | Primera A | |
| Away game | Independiente Medellin | 0 | 2 | America de Cali | Home game | Primera A | |
| Away game | Independiente Medellin | 0 | 1 | America de Cali | Home game | Primera A | |
| Home game | Independiente Medellin | 1 | 4 | America de Cali | Away game | Primera A | 
- PLAYED
 - 5
 
- WINS
 - 0
 
- GOALS
 - 3:9
 
- GOALS / MATCH
 - 0.60
 
- Independiente Medellin lost three times in head-to-head matches
 - Teams played five times head-to-head in the current season with the goals score 3:9; average goals per match – 0.60
 
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