- 16 September 2026, Columbus Crew vs Orlando City SC, 2-1, Win
- 20 May 2026, Columbus Crew vs New York City FC, 1-0, Win
- 29 April 2026, Columbus Crew vs One Knoxville SC, 4-1, Win
- 15 April 2026, Richmond Kickers vs Columbus Crew, 0-3, Win
- 24 May 2023, Pittsburgh Riverhounds vs Columbus Crew, 1-0, Lose
- 17 September 2026, Colorado Rapids vs St Louis City SC, 0-3, Win
- 20 May 2026, St Louis City SC vs Houston Dynamo, 6-4, Win
- 30 April 2026, Chicago Fire vs St Louis City SC, 1-2, Win
- 16 April 2026, St Louis City SC vs Tulsa Roughnecks FC, 4-0, Win
- 21 May 2025, Minnesota United FC vs St Louis City SC, 3-2, Lose
Form Guide
| Win | 2-1 | Columbus Crew vs Orlando City SC | |
| Win | 1-0 | Columbus Crew vs New York City FC | |
| Win | 4-1 | Columbus Crew vs One Knoxville SC | |
| Win | 0-3 | Richmond Kickers vs Columbus Crew | |
| Lose | 1-0 | Pittsburgh Riverhounds vs Columbus Crew |
- PLAYED
- 5
- WINS
- 4
- GOALS
- 10:3
- GOALS / MATCH
- 2
- Columbus Crew has four wins in its last five matches with a goal difference of 10:3, scoring 2 goals average
| Win | 0-3 | Colorado Rapids vs St Louis City SC | |
| Win | 6-4 | St Louis City SC vs Houston Dynamo | |
| Win | 1-2 | Chicago Fire vs St Louis City SC | |
| Win | 4-0 | St Louis City SC vs Tulsa Roughnecks FC | |
| Lose | 3-2 | Minnesota United FC vs St Louis City SC |
- PLAYED
- 5
- WINS
- 4
- GOALS
- 17:8
- GOALS / MATCH
- 3.4
- St Louis City SC has four wins in its last five matches with a goal difference of 17:8, scoring 3.4 goals average
Columbus Crew H2H St Louis City SC
| Away game | Columbus Crew | 2 | 1 | St Louis City SC | Home game | MLS | |
| Home game | Columbus Crew | 2 | 1 | St Louis City SC | Away game | Leagues Cup |
- PLAYED
- 2
- WINS
- 2
- GOALS
- 4:2
- GOALS / MATCH
- 2.00
- In the last two matches that these two sides meet, Columbus Crew overtook St Louis City SC twice
- Columbus Crew won twice
- Teams played two times head-to-head in the current season with the goals score 4:2; average goals per match – 2.00
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