- 12 August 2025, Leyton Orient vs Wycombe Wanderers, 0-1, Lose
- 17 September 2024, Brentford vs Leyton Orient, 3-1, Lose
- 27 August 2024, Millwall vs Leyton Orient, 0-1, Win
- 13 August 2024, Leyton Orient vs Newport County, 4-1, Win
- 08 August 2023, Plymouth Argyle vs Leyton Orient, 2-0, Lose
- 27 August 2025, Oxford United vs Brighton and Hove Albion, 0-6, Lose
- 12 August 2025, Oxford United vs Colchester United, 1-0, Win
- 27 August 2024, Coventry City vs Oxford United, 1-0, Lose
- 13 August 2024, Oxford United vs Peterborough United, 2-0, Win
- 09 August 2023, Bristol City vs Oxford United, 5-1, Lose
Form Guide
| Lose | 0-1 | Leyton Orient vs Wycombe Wanderers | |
| Lose | 3-1 | Brentford vs Leyton Orient | |
| Win | 0-1 | Millwall vs Leyton Orient | |
| Win | 4-1 | Leyton Orient vs Newport County | |
| Lose | 2-0 | Plymouth Argyle vs Leyton Orient |
- PLAYED
- 5
- WINS
- 2
- GOALS
- 6:7
- GOALS / MATCH
- 1.2
- Leyton Orient has two wins in its last five matches with a goal difference of 6:7, scoring 1.2 goals average
| Lose | 0-6 | Oxford United vs Brighton and Hove Albion | |
| Win | 1-0 | Oxford United vs Colchester United | |
| Lose | 1-0 | Coventry City vs Oxford United | |
| Win | 2-0 | Oxford United vs Peterborough United | |
| Lose | 5-1 | Bristol City vs Oxford United |
- PLAYED
- 5
- WINS
- 2
- GOALS
- 4:12
- GOALS / MATCH
- 0.8
- Oxford United has two wins in its last five matches with a goal difference of 4:12, scoring 0.8 goals average
Leyton Orient H2H Oxford United
| Away game | Leyton Orient | 2 | 1 | Oxford United | Home game | League One | |
| Home game | Leyton Orient | 2 | 3 | Oxford United | Away game | League One | |
| Away game | Leyton Orient | 0 | 5 | Oxford United | Home game | EFL Trophy | |
| Away game | Leyton Orient | 1 | 0 | Oxford United | Home game | League Two | |
| Home game | Leyton Orient | 2 | 2 | Oxford United | Away game | League Two |
- PLAYED
- 5
- WINS
- 2
- GOALS
- 7:11
- GOALS / MATCH
- 1.40
- In the last five matches that these two sides meet, Leyton Orient overtook Oxford United twice
- Leyton Orient won twice, lost twice and had one draw
- Teams played five times head-to-head in the current season with the goals score 7:11; average goals per match – 1.40
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